Major Components for Lipodisslove

     - Phosphatidylcholine, which occurs naturally in the body as a component of cell membranes. It's also sold as a food supplement called lecithin. Lecithin shows up in egg yolks, soybeans, fish and other foods. The form used for Lipodissolve is mainly extracted from soybeans.

     - Deoxycholate,which is a "bile acid," a solvent that the liver secretes to break up fat that enters your small intestine.

     So these are natural substances and chemicals, long used in Europe, though not yet approved by the FDA for fat injections in the USA.

     The compounds used for lipodissolve have not been approved or intensely tested by the U.S. Food and Drug Administration for any sort of fat reduction. That means it is off-label or an unregulated use. “Off-label” means that it has been approved or occurs naturally for one purpose, but doctors are using it for a different purpose. Off-label use of drugs is very common. The medical community has a history of such medication use if the off-label treatment is similar to the approved treatment.

     For example, using Botox® to remove wrinkles is an off-label treatment. Botox is approved to relieve muscle spasms due to neurological problems. Another example, is using an antibiotic that may be approved for treating a bladder infection for a different area, such as, a sinus infection (this type of substitution or use has been done frequently by physicians for years). Also, a cancer drug may be approved for one cancer, but used off-label for another cancer, if common medical practice or experience suggests a beneficial effect, without formal approval from the FDA. As a practical matter, often it is just too time consuming or expensive to seek approval for every indication for a product from the FDA.

Off-label use of a drug is legal unless specifically banned by the FDA.

What should I expect during LipoDissolve treatment?

     The clinic uses a very small and sharp needle about the size of the ones used for insulin injections. A treatment consists of multiple small injections that surround the fat pad or fat accumulation. The doctor determines the amount and percentage of the compound needed to be injected.

     After the injections the patients can often return immediately to their normal routine. The procedure literally can be done during a lunch break (about a 30 minute session). Some people would prefer to take the remainder of the day off or do it around a weekend when off.

Are there any possible side-effects?

In the first two or three days, patients may feel some localized discomfort and a heat sensation in the area, which may redden or even bruise (not uncommon to look like an area after blood is drawn from your arm at a lab). The tissue beneath the skin can temporarily harden some; it may feel like there are small cysts about the size of a marble in the area of injections (these go away).

The fat cells can actually seem to enlarge for about a week after the injections due to inflammation and edema, but those bumps are the death throes of the fat cells. Eventually, the fat cells dissolve and are flushed from the body as we pass other forms of waste. Various research on lipid studies have not shown any significant
hemodynamic changes during the post injection or flushing process.

In Europe, LipoDissolve has been popular since 1995 and mesotherapy has been used since the 1950's and thousands and thousands of injections have been done. Searches of literature show generally only minor expected adverse reactions. Presently, it is estimated that over 15,000 medical practitioners provide injections throughout Europe, Great Britain and South America. It is estimated that there are 500 to 1000 doctors or clinics in the USA doing this therapy.